Medical News, Myanmar

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Medical News, Myanmar @beautymm_com: Latest medical news from Myanmar

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Population pharmacokinetics of dihydroartemisinin and piperaquine in pregnant and non-pregnant women with uncomplicated malaria.
Tue, 17 Jan 2012 05:00:00 +0100 | Antimicrobial Agents and Chemotherapy
The objective of this study was to evaluate the population pharmacokinetic properties of piperaquine and dihydroartemisinin in pregnant and non-pregnant women with uncomplicated malaria. Twenty four pregnant and 24 matched non-pregnant women on the Thai-Myanmar boarder were treated with a standard fixed oral 3-day treatment and venous plasma concentrations of both drugs were measured frequently for pharmacokinetic evaluation. Population pharmacokinetics was evaluated with nonlinear mixed-effects modelling. The main pharmacokinetic finding was an unaltered total exposure of piperaquine but a 38% lower total exposure of dihydroartemisinin in pregnant compared to non-pregnant women with uncomplicated malaria. Piperaquine was best described by a three-compartment disposition model with a 45% h...

Malaria in South Asia: Prevalence and control.
Sun, 08 Jan 2012 05:00:00 +0100 | Acta Tropica
Authors: Kumar A, Chery L, Biswas C, Dubhashi N, Dutta P, Dua VK, Kacchap M, Kakati S, Khandeparkar A, Kour D, Mahajan SN, Maji A, Majumder P, Mohanta J, Mohapatra PK, Narayanasamy K, Roy K, Shastri J, Valecha N, Vikash R, Wani R, White J, Rathod PK Abstract The "Malaria Evolution in South Asia" (MESA) program project is an International Center of Excellence for Malaria Research (ICEMR) sponsored by the US National Institutes of Health. This US-India collaborative project will study the origin of genetic diversity of malaria parasites and their selection in the Indian subcontinent. This knowledge should contribute to a better understanding of unexpected disease outbreaks and unpredictable disease presentations from Plasmodium falciparum and Plasmodium vivax infections. In this firs...

SNP Genotypes of Mycobacterium leprae Isolates in Thailand and Their Combination with rpoT and TTC Genotyping for Analysis of Leprosy Distribution and Transmission.
Sun, 01 Jan 2012 05:00:00 +0100 | Japanese Journal of Infectious Diseases
Authors: Phetsuksiri B, Srisungngam S, Rudeeaneksin J, Bunchoo S, Lukebua A, Wongtrungkapun R, Paitoon S, Sakamuri RM, Brennan PJ, Vissa V Abstract Based on the discovery of three single nucleotide polymorphisms (SNPs) in Mycobacterium leprae, it has been previously reported that there are four major SNP types associated with different geographic regions around the world. Another typing system for global differentiation of M. leprae is the analysis of the variable number of short tandem repeats within the rpoT gene. To expand the analysis of geographic distribution of M. leprae, classified by SNP and rpoT gene polymorphisms, we studied 85 clinical isolates from Thai patients and compared the findings with those reported from Asian isolates. SNP genotyping by PCR amplification and s...

The infectivity and pathogenicity of a foot-and-mouth disease virus persistent infection strain from oesophageal-pharyngeal fluid of a Chinese cattle in 2010
Wed, 14 Dec 2011 05:00:00 +0100 | Virology Journal
Conclusion: The persistent infection strain O/CHN/2010/33-OP has infectivity and pathogenicity to cattle and pigs, and infected cattle may transmit the virus to pigs although its virulence was lower than the circulated strain O/CHN/Mya98/2010. (Source: Virology Journal)

Identification of the Geographic Origin of Dendrobium thyrsiflorum on Chinese Herbal Medicine Market Using Trinucleotide Microsatellite Markers.
Tue, 13 Dec 2011 19:42:03 +0100 | Biological and Pharmaceutical Bulletin
Authors: Yuan YH, Hou BW, Xu HJ, Luo J, Ding XY Abstract The stems of Dendrobium thyrsiflorum RCHB.F. ex ANDRé can be processed into an important class of Traditional Chinese Medicine named "Huangcao Shihu," which has diverse curative effects, such as nourishing yin and clearing away unhealthy heat, benefiting the stomach, and promoting the production of body fluid. The identification of the geographical origin of D. thyrsiflorum is vital for preserving its natural resource and ensuring the quality of "Huangcao Shihu." In order to identify the origin of D. thyrsiflorum on Chinese herbal medicine market, 14 D. thyrsiflorum-specific microsatellite markers were developed in this study. Assignment tests were performed by the microsatellite marker analysis coupled with three new statis...

Virulence Factors and Genetic Characteristics of Methicillin-Resistant and -Susceptible Staphylococcus aureus Isolates in Myanmar
Thu, 01 Dec 2011 15:52:57 +0100 | Microbial Drug Resistance
Microbial Drug Resistance Dec 2011, Vol. 17, No. 4: 525-535. (Source: Microbial Drug Resistance)

Mystery bird: Malay eagle-owl, Bubo sumatranus | @GrrlScientist | Punctuated Equilibrium
Fri, 14 Oct 2011 16:30:01 +0100 | Guardian Unlimited Science
This southeast Asian mystery bird is part of a family whose taxonomic relationships are still unresolved Malay eagle-owl, Bubo sumatranus (formerly, Bubo sumatrana; protonym, Strix Sumatrana), also known as the Malaysian eagle-owl, the Oriental eagle-owl, or as the barred eagle-owl, photographed at Taman Negara, Malaysia. Image: Kadambari Devarajan, June 2011 (with permission) [velociraptorize].Sony A550, Sigma 150-500mm, ISO 1600, 1/250 second, f/5, focal length 200mm Question: This southeast Asian mystery bird is part of a family whose taxonomic relationships are still unresolved. Can you identify this bird's taxonomic family and species? What might be the function of those funny-looking "horns" on this bird's head?Response: This is a Malay eagle-owl, Bubo sumatranus, a resident of mois...

MSF reluctantly withdraws after 35 years
Thu, 06 Oct 2011 13:48:00 +0100 | MSF News
After months of negotiations and discussions with Thai authorities, it has proved impossible to get permission to provide healthcare to the undocumented migrants and vulnerable populations in Thailand that Médecins Sans Frontières (MSF) believes are the most in need of medical assistance. MSF has therefore been forced to close its projects in Samut Sakhon and three Pagodas Pass, depriving 55,000 vulnerable people of their only access to healthcare. This September, MSF came to the conclusion that the medical organization had no choice but to close its longest-running mission, which started with the provision of assistance to Cambodian refugees fleeing the Khmer regime in 1976. Thailand © Francesca Di BonitoMSF staff conduct vaccinations at a camp in northern Thailand for Hmong refuge...

Which is the best health system in the world?
Tue, 04 Oct 2011 04:00:00 +0100 | BMJ Online First
According to the World Health Organization, the country with the best health system overall in the world in 2000 was France, with the UK ranked 18th and Burma (Myanmar) coming last at 190th.1 In... (Source: BMJ Online First)